Nucleic Acid Engineering (2017 spring)
Research area
- Nucleic acid bioengineering
- Microarray technology
- Electrochemical diagnostics
- Nanobiotechnology
Current project
HOME > Research > Research area > Electrochemical diagnostics


Novel electrochemical technologies for genetic diagnostics


We are developing various electrochemical detection methods for genetic diagnosis. First, novel electrochemical strategies to detect nucleic acids were developed utilizing neutral charge property of peptide nucleic acid (PNA)

or unique binding property of DNA intercalating agent. Second, a new detection method of DNA mutation or

SNP genotyping was developed based on mismatched DNA-specific cleavage activity of CEL I endonuclease.

These results developed by our group will serve as the basis for advanced electrochemical strategies for genetic diagnosis. In addition, we are currently developing the electrochemical real time PCR method.